As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world. UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a "Great College to Work For" for four consecutive years.The Department of Urology at the University of Washington consistently ranks among the top urology programs in the country. Our four word motto reflects our mission: Cure, Comfort, Teach, and Wonder. As a clinical department, our emphasis is "to cure the patient when possible and comfort always". This preoccupation applies not only to routine urologic management but also to the difficult and/or unusual conditions requiring special knowledge and skill. In addition, all professional members of this department have embraced this motto because they wish to teach didactically and by example. This teaching involves medical students, resident physicians, and surgeon fellows in a way that enhances the care of the patient. Finally, most people are in academic medicine because they are intellectually fascinated with the Wonder of medical biology and human nature. Clinical and applied laboratory research is a major mission of this department and its national ranking is in part because of outstanding research productivity in many urologic subspecialties including cancer, infection, pediatrics, sexual function, transplantation, trauma, and women's healthcare. As such, another major focus of the department is to train urologic researchers and surgeon scientists for the future.The Department of Urology currently has an outstanding opportunity for a RESEARCH PATHOLOGIST.The purpose of this position is to promote the research objectives of the multidisciplinary Urological Oncology program at the University of Washington. This position works with the Genitourinary (GU) Cancer Research Laboratory in the Department of Urology at the University of Washington. The Research Pathologist will work with faculty and staff both collaboratively and independently on multiple research projects.Metastatic cancer is heterogeneous in its biological features and molecular characteristics making treatment responses of advanced disease difficult to predict and manage. To confront this challenge it is necessary for research investigators to have a portfolio of tumor tissues for study that mimic the diversity of the disease seen in various clinical situations. Accordingly, the GU Cancer Research Laboratory has engaged in a comprehensive effort to acquire, process, store, and utilize such tumor tissue from the operating room and from a Rapid Autopsy Program. The Rapid Autopsy Program has been especially valuable to these research efforts as it allows us to perform an autopsy within hours of death of consenting patients who expire with advanced disease thus allowing the acquisition of metastatic prostate and bladder cancer.Duties and Responsibilities:The Research Pathologist will evaluate and perform prostate cancer research using standardized cellular and biochemical techniques and novel experimental approaches. Perform research under limited direction of Lab's Primary Investigator (PI). The applicant will develop novel research methods to investigate the conversion of adenocarcinoma to neuroendocrine phenotypes and to understand the molecular mechanisms that regulate maintenance and differentiation of prostate cancer phenotypes, as well as perform routine scientific work, evaluating, selecting and applying standardized and modified scientific procedures and techniques to assignments with clear, specific objectives.Laboratory and Experimental Research:Phenotype and analyze clinical biospecimens and model systems; Isolate samples by laser capture microdissection or grossly for downstream experiments using molecular techniques including Western Analysis, qPCR, RNAseq, and protein arrays;Assess biomarker expression using standard and multiplex immunohistochemistry (IHC) techniques;Process specimens for specific projects;Work with team to draft and review manuscriptsCollaborative Research and Laboratory Data Management:Participate in the laboratory's rapid autopsy program involving patients who have expired with advanced prostate or bladder cancer, which will require the applicant to be on-call and provide services outside of normal duty hours;Work with collaborators to assess new technologies;Use skills in microphotography, including the use of Photoshop, to generate data for publication;Work with collaborators to analyze raw data and convert into presentation quality figures, graphs, tables, and methods for publication; *Ensure the quality control of data by keeping highly organized notebooks, spreadsheets and databases of research data;Participate in weekly meetings with the principle pathologist and tissue acquisition team to develop and improve the tissue acquisition process and assess pathology of all specimens acquired by the laboratory;Have a flexible approach, can liaise with PIs on specific projects, and interacts in a highly collaborative and professional manner with other team members and collaborating investigators. Minimum Requirements:Masters Degree in Pathology and three to five years of experience. Advanced training in Pathology in addition to experience can substitute for education requirement. US Board Certification in Pathology is not required.Knowledge of Excel and Access with an ability to make figures and graphsFamiliarity with microscopic photographyHighly efficient at multi-taskingDemonstration of leadership and professionalismDesired:MD, or MD equivalent (including foreign equivalency).Conditions of Employment:Candidate must be willing to work with biohazards, including, but not limited to, human and animal tissues and their bodily fluids. The candidate will be required to participate in the Occupational Health Program. The candidate will be required to attend, participate, and pass (where required) the University of Washington's training courses in Bloodborne Pathogens, and additional courses as required for successful completion of job duties. Regular and predictable attendance is required.Application Process:The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.